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Excess amino acids, equally from protein degradation in the absence protein synthesis — a disruption in the balnace concerning protein synthesis and protein degradation — and dietary input are degraded, causing an increase in ammonia and ammonium ion, which happen to be converted to urea for disposal.
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Destructive nitrogen stability — nitrogen intake < nitrogen excreted: Detrimental nitrogen balance happens when excess amino acids are metabolized making increased ammonia and ammonium ion, and may result from several conditions: inadequate dietary protein
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If negative nitrogen balance persists for too lengthy, physique perform is impaired due to the Internet loss of vital proteins